Research Scientist Position - Synthetic Chemist / Medicinal Chemist:

Job Code: MB-SCM-001

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We are seeking a full-time Synthetic organic/Medicinal chemist with expertise in synthesizing organic molecules and isolation and purification of molecules/metabolites from complex matrices. The ideal candidate is obsessed with the question of how to best in synthesizing and modifying the microbial products. This is a unique opportunity to work at a nimble, forward-thinking microbiome startup and help build the foundation for microbiome as therapeutics.

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Job responsibilities:

  • Develop and perform LC-UV/MS and HRLC-MS/MS method development and quantification of metabolites from complex matrices

  • Develop and perform extractions, isolation, and purification of natural products from fermentation cultures

  • Synthesize and modify the isolated products

  • Analyze and characterize purified compounds by various techniques including TLC, LC-MS, and NMR

  • Review current literature and contribute novel ideas to guide the pre-clinical development of novel microbiome-based products 

  • Document work in notebooks and technical reports 

  • Prepare presentations for internal meetings 

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Candidate Must: 

  • Possess excellent oral and written communication skills 

  • Contribute effectively in a cross-functional role and serve as a subject-matter expert

  • Demonstrate ability to work independently and as part of a team consisting of a diverse group of science professionals 

  • Work well within a fast-paced, dynamic, and team-oriented start-up environment 

  • Possess excellent organizational, interpersonal and problem-solving skills 

  • Demonstrated skills in laboratory techniques

  • Knowledge of safe laboratory practices, including the proper procedures in handling chemicals and samples

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 Qualifications: 

  • Ph.D. in Synthetic Organic Chemistry or Medicinal Chemistry required 

  • Ideally 2 to 5 years of hands-on post-doc experience or industrial experience

  • Strong background in synthetic organic chemistry, reaction mechanisms, and natural products chemistry or related field 

  • Skilled in developing the scalable synthetic routes for potential leads and design and synthesize target molecules

  • Additional experience in scale-up of samples for in-vivo and ex vivo studies

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